Which body structure is predominantly affected by neuropathy?

Neuropathy primarily affects the nerves, which is why the correct answer is the choice indicating nerves. Neuropathy is characterized by damage or dysfunction of peripheral nerves, leading to a range of symptoms including pain, tingling, numbness, and muscle weakness. This condition can result from various factors such as diabetes, infections, or systemic diseases, but its fundamental nature involves the impact on nerve function.

In contrast, while muscles, skin, and the brain may be indirectly influenced by neuropathy (as the nerves are responsible for communicating signals to these structures), they are not the primary targets of the condition itself. Muscles may weaken due to neuropathy affecting the motor nerves, and skin sensations may be altered if sensory nerves are involved, but the root issue lies within the nerves themselves. Thus, recognizing that neuropathy directly affects the nerves clarifies why this is the correct choice.