What psychological phenomenon often accompanies withdrawal from a substance?

Craving is a psychological phenomenon that frequently occurs during withdrawal from a substance. This intense desire or urge to consume the substance is a hallmark of addiction and can manifest as a significant emotional response when the substance is no longer available. The brain's chemistry shifts during substance use, and when the substance is withdrawn, it can lead to a dysregulated state, heightening the feeling of craving. This desire can drive individuals back to substance use as a means of alleviating the discomfort associated with withdrawal symptoms, making it a critical concept in understanding addiction and recovery.

The other options, while related to substance use, serve different roles in the context of withdrawal. Loss of control can be a characteristic of substance abuse but is not specific to the withdrawal phase. Euphoria typically refers to the pleasurable sensations experienced while under the influence of a substance, rather than during withdrawal. Increased tolerance, which is the body's adaptation to a substance that leads to needing more of it to achieve the same effects, does not directly relate to the withdrawal experience itself. Thus, craving stands out as the most relevant psychological phenomenon accompanying withdrawal.